Publication: Toward a Unified Lexicon in Traumatic Brain Injury
Toward a Unified Lexicon in Traumatic Brain Injury: Defining the Mechanism of Injury
This recent PANTHER publication in Neurotrauma Reports admonishes the use of precise and consistent wording to define the mechanism of injury at the cellular scale. The authors argue that primary and secondary injury should be defined as distinct biological cellular mechanisms.
We propose that at the cellular scale, standardizing the definitions of primary and secondary injury as distinct biological mechanisms—rather than sequential stages—can help advance our understanding of TBI, facilitate interdisciplinary collaboration, and enable more effective comparisons across experimental models, ultimately leading to improved diagnosis and treatment strategies.
